As the life science industry moves from conventional biologics to advanced therapy medicinal products (ATMPs) such as cell and gene therapies, facilities must evolve to accommodate these new processes. Developers and biotechs alike may be wondering how to adapt their existing spaces and what an ideal facility looks like. FPBA’s Executive Vice President Andy Darragh provides insight on cell and gene therapy facility design below. Want to learn more or speak to someone at FPBA about cell and gene therapy facility design? Get in touch with us using the below form, and we will respond promptly.
Adapting Your Facility to COVID-19 Measures
As life science companies race to develop vaccines and treatments for COVID-19, they have become known as leaders and experts in navigating the pandemic. However, many biotechs face the same questions as other businesses when it comes to preparing their facilities to address COVID-19 and mitigate spread. Biocom’s “Adapting Your Facility to COVID-19” workshop, held virtually on June 23, 2020, tackled the subject head-on. Moderated by Jeana Renger, Vice President at Ferguson Pape Baldwin Architects, the workshop explored best practices for facility managers in adapting to COVID-19, joined by panelists Jessica Francis from Fate Therapeutics, Taylor Gifford from Cultura, and DJ VanSlogteren from Siemens, as well as Biocom Facilities Committee Co-Chairs Jason Moorhead from ARE and Andy Darragh from FPBA. The discussion covered workplace design to accommodate physical distancing; people flows, monitoring density, and limiting occupancy; seat assignments with staggered shifts; smart cleaning; digital contact tracing; touchless entry; and sterilization through UV lighting. A Model of Excellence: COVID-19 Onsite Operations at Fate Therapeutics Fate Therapeutics, a biopharmaceutical company that develops cellular immunotherapies for cancer and immune disorders, was early to respond to COVID-19. According to Jessica Francis, Executive Director, HR & Operations at Fate Therapeutics, the company prohibited business travel in January, increased facility cleaning in February, and rolled out a work-from-home plan and staggered schedules for essential workers in early March. At the beginning of June, Fate doubled its capacity to perform lab and manufacturing work, from 35 percent to 70 percent, while work that can be conducted from home remains at home. To accomplish this capacity increase, Fate is expanding office space at a new location to allow for physical distancing, as well as implementing the following infection control practices: Physical Distancing: Maintain 6 feet distance when possible, prohibit discussions in tight areas, increase space between workspaces, reassign seating to limit close contact, temporarily close off conference rooms Personal Protective Equipment (PPE) Requirements: Use facial coverings in all on-site areas, unless in an office area alone, or eating with no one else around Disinfection, Sanitation and Airflow: Day porter wipes down surfaces twice daily, janitorial staff disinfects every evening, hand sanitizer and disposable wipes are placed throughout Managing Traffic Flow: Place maps, signage and recommended routes for entering and exiting labs, break rooms and offices; prohibit congregating in shared areas; use outdoor spaces for breaks; and temporarily convert conference rooms to desk spaces Meetings: Conduct meetings virtually when possible, limit in-person meetings to two people for no more than 30 minutes, prohibit business travel, report personal travel, limit visitors to essential workers such as UPS and vendors Health Monitoring/Reporting Requirements: Screen on-site employees daily, prohibit going into work if an employee or household member displays symptoms or has been in contact with someone who has been diagnosed with COVID-19, maintain confidentiality Case-by-Case Accommodations: Employees encouraged to contact HR if they are unable to return to on-site work, work that can be conducted from home should continue to be, ergonomic solutions provided as needed Incidence Response: Create incidence response plan where incidence response team is informed of potential employee exposures, direct exposed employee to self-isolate, conduct contact tracing, notify potential exposed employees, close impacted areas of the facility for 24 hours to conduct deep cleaning, maintain confidentiality Francis recommended communicating constantly regarding proper use of masks and conference room closures, providing a dedicated place for these communications. “We developed a COVID-19 resource page on our intranet and we update the Frequently Asked Questions and post all communications there,” Francis said. “Regular email messaging wasn’t enough.” Comeback Strategy: Supporting Wellbeing, Preserving Culture, and Transforming the Furniture Plan While Francis gave a comprehensive look into the operational side of adapting to COVID-19, Taylor Gifford, Vice President at Cultura, presented options for how to make adjustments to accommodate physical distancing while supporting wellbeing and preserving company culture in various spaces. “You want to establish a sense of confidence with your organization through the space that you’re utilizing,” Gifford said. Effective policies and procedures that outline what employees can and cannot do will give them the confidence to come back to the office. To start out, Gifford brought up a floor plan overlaid with green and red. Green areas were “Good to Go,” meaning those workspaces already accommodate a 6-foot distance. Red areas meant they “Need Attention” and must be rearranged to account for 6 feet of separation. Most red areas were meeting rooms and shared spaces, but some benching system workstations were also culprits of closeness. “It’s not uncommon to find a lot of red, and this can seem overwhelming at first,” Gifford said. You have to analyze who these workers are, what they are doing, and whether they are splitting their time between their desk and the lab. Once you have a better understanding of how the spaces are used, you can reassess the floor plan and consider shift scheduling. Reconfiguring the space does not necessarily mean shutting down the open office or benching spaces. Instead, Gifford says, it could be assigning workspaces diagonal from each other with a staggered schedule, removing some chairs from conference rooms, rotating chairs away from each other, and adding divider panels to workstations for privacy and protection. Flexible furniture such as conference tables that can be pulled apart into smaller pieces allow for separation and put the power into employees’ hands. “People want some user control right now,” Gifford said. “It’s a good way to give them a sense of confidence and safety.” Cleanability of furniture materials should also be considered. Hard and seamless surfaces are easier to clean than porous ones, while Alta, a water and stain repellent, can be applied to fabrics to enhance cleanability. Ultimately, Gifford emphasized that companies should gather information from employees on what makes them feel safe before rushing out to buy a bunch of plastic dividers. Cultura was a major contributor to Biocom’s Return to Work Guide for California’s Life Science Industry, which offers a deep dive into preparing for the return to work. … Read more »
FPBA celebrates groundbreaking of The Boardwalk with virtual reality, shiny shovels and lab-themed cuisine
With virtual reality, branded golden shovels, and science-themed catering, The Boardwalk project team—FPBA, Healthpeak, PMA, Swinerton, CBRE and others—gathered at Science Center Drive on Jan. 9, 2020, to commemorate the groundbreaking of a 195,000 SF research campus many years in the making. This groundbreaking was not your average shoveling of dirt. With virtual reality headsets, FPBA brought an immersive experience that allowed attendees to step into the campus and see it in 360 degrees. An animated reel and renderings further depicted the vision of The Boardwalk. “This is really meant to be a flagship asset for Healthpeak down here in San Diego,” said Mike Dorris, Vice President of Healthpeak. “We really strived to try to create a project that is going to be not only appreciated by the tenants that ultimately occupy the project but also the community at large.” [URIS id=4952] Clique Hospitality catered a sampling of the menu to be offered at The Boardwalk’s full-service restaurant—including laboratory-themed offerings such as bubbly libations served in beakers and crab hand rolls fitted with soy-sauce-filled pipettes. The dining experience was a tasty reminder that The Boardwalk will be a charming spot to be enjoyed by the overall community. Swinerton provided elegant golden shovels branded with The Boardwalk logo to mark the occasion. CBRE matched the life-sized tools with miniature shovel-shaped bottle openers as a take-home memento. The commemoration was a coming together of a team that is proud of the work they have put into this vision, and excited to begin making that vision a reality. FPBA has been involved in repositioning this campus for nearly 10 years, executing many design iterations to reach the ultimate design that will be built out. The Boardwalk will connect three buildings with a wooden circulation path to create a unified campus experience—featuring amenities like a full-service restaurant, one-acre park and expansive conference center. “What started as two distinct buildings on separate land sites has now morphed into an aesthetically cohesive, three-building, amenity-rich campus,” Dorris said. “It’s a project that’s going be functional for the life science community that we have here in San Diego, but it’s also just a really aesthetically pleasing, elegant design.” FPBA is thrilled to continue working with Healthpeak, PMA and Swinerton during construction and see the design come to fruition. More information on The Boardwalk can be found here.
FPBA celebrates topping out of NuVasive Lusk Campus Amenities Building
On December 19, 2018, FPBA celebrated the topping out of the NuVasive Lusk Campus Amenities Building. FPBA team members Phil Pape, Carlos Ortuño, Derek McFarland, Stefanie Deal and Iisha Sethi left their mark on the building’s final beam, which was painted a symbolic NuVasive purple. The beam was also adorned with a paw print from Cheetah—the NuVasive mascot—along with signatures from PMA, Pacific Building Group, KPFF, ELEN and more. Following tradition, an American flag and in-season Christmas tree put the finishing touches on the beam. [URIS id=4539] The team enjoyed panoramic views and munched on Hodad’s burgers while watching the raising of the beam from the top of the adjacent parking structure. The three-story, 28,000-square-foot amenities building will house a surgical suite, fitness center, conference center, full-service cafeteria, product discovery center, and campus reception, supporting the medical device company’s mission of transforming spine surgery. FPBA is proud to partner with HCP and NuVasive. In addition to the amenities building, FPBA is providing site improvements to the 15-acre campus, which will create a new entry promenade, outdoor cafeteria space/overflow seating, entertainment zone and outdoor collaboration space. The three existing building exteriors will be upgraded to complete the improved campus experience.