Sorrento Therapeutics is an antibody-centric, clinical stage biopharmaceutical company focused on the discovery and development of safe and effective immunotherapies for oncology and autoimmune/inflammation diseases. The company’s acquisition of several companies drove the need to expand its facilities and bring these acquisitions under one roof in a leased 75,000-square-foot building. The project included renovation of existing labs, offices and a lobby, along with new designs for labs, offices, a vivarium, a lunch room, a lunch patio and a board room. Sorrento’s scientific groups included bacteria, infectious disease, oncology/immunology, TNK, LA Cell, and chemistry, some of which were new groups within the company. Ferguson Pape Baldwin Architects worked closely with these groups to establish a common lab module that would meet their specific needs but also be flexible for groups to expand and share space as they grow within two large open laboratories. This included the chemistry lab, which required segregation for safety and contamination control. FPBA assisted with capturing equipment information for legacy equipment coming from several different locations and consolidated shared equipment in centrally located support rooms to save space and money. The project was constructed in three phases on a fast-track schedule with successive occupancy dates. FPBA coordinated the approvals for this phasing with the building officials using a single set of permit drawings and obtained the permit in just four weeks to complete design and start construction ahead of schedule.
Cymer, the largest supplier of deep ultraviolet (DUV) light sources, sought to expand its existing facility by adding a full-service kitchen and café for employees and visitors to enjoy. The expansion is an addition to the 134,000-square-foot facility designed by FPBA in 1999. The vibrant space is flooded with expansive light from the north-facing glazing and three clerestory bays. An operable glass wall allows the assembly space to spill out on to the exterior courtyard and double as overflow seating for large company gatherings. Comfort and energy efficiency are weaved into the space with passive cooling systems via large ceiling fans and lighting controls that automatically dim artificial lighting when natural daylight is available. The dynamic roof line evokes the spirit of the existing shell and forms the volumetric space of the addition — embodying the lively culture of Cymer’s San Diego Headquarters.
Project SHORE (Shire Operations for Regenerative Expansion) was master planned to be a new build-to-suit campus for Shire’s Regenerative Medicine Business Unit and provide increased commercial production capacity of Dermagraft, a dermal substitute approved for treatment of diabetic foot ulcers, along with future capacity for other products. The master plan includes an ultimate build out of up to 850,000 square feet on 28 acres. Phase 1 of the project comprised two buildings totaling 350,000 square feet. The Technical Operations Building includes Manufacturing, Laboratory, Warehouse, Distribution, and Central Utility space. A Commercial Operations Building was designed to house Administrative Offices, a Full-Service Cafeteria, a Fitness Center, a Training Room and Conference Rooms. A pedestrian tunnel with enhanced artwork was designed to safely connect the two parcels underneath the road. The project was developed using a High Performance Team (HPT) with the owner, project managers, contractors, sub-contractors, architects and engineers co-located in a large trailer complex on the site. This supported a highly coordinated team effort with a mission statement and core values created by the HPT Board of Directors to foster trust and guide the culture of the entire project team. This team utilized a very high level of Building Information Modeling (BIM) to improve coordination of building systems and utilize best practices for efficient project delivery. FPBA processed over 20 permits to support the fast-tracked schedule including overall entitlements, grading, steel frame, tunnel, shell and tenant improvement building permits. Although the project construction ended before completion, design documentation was fully complete and many of the High Performance Team methodologies were tested during the first phases of construction. This project will be a model for project delivery excellence in the industry.
Gilead Sciences commissioned this project to further its commitment to advancing therapeutics in the quest to improve lives. With over 23 acres in an industrial and manufacturing park in Southern California, Phase 1 is designed for 320,000 usable square feet in five buildings with generous vertical clearances to accommodate manufacturing equipment. The complete campus build-out is master planned for over 600,000 square feet. The facility includes large-scale sterile pharmaceutical manufacturing, lypohilization and final filling in ISO 5 to ISO 8 clean rooms. Tablet and vial packaging lines package and label products made at this site and at contract manufacturing sites across the nation. The lab-office building houses a full-service cafeteria and fitness center, along with QC, validation and manufacturing technical support laboratories. The building materials are of supreme quality, including GFRC panels, concrete, metal and glass. These materials create texture, relief and colors for a richer architectural look. The resulting architecture conveys a clean, modern aesthetic for one of the world’s leading pharmaceutical companies.
Gilead Sciences opened its new site in Oceanside by purchasing an existing clinical-scale manufacturing building. Ferguson Pape Baldwin Architects was tasked with creating a campus environment when Gilead acquired the adjacent building to house laboratories and office space. The new site improvements created accessible pedestrian access and landscaping to tie the two buildings together, and the new glass storefront at the lobby entrance provided more natural light. The interior space was master planned to create a mezzanine for utilities and to preserve critical space for a future pilot plant, more labs and offices. Conference rooms, multi-purpose space, a cafeteria and fitness center were added to provide the amenities that had previously been lacking.
Gilead Sciences opened its new site in Oceanside by purchasing an existing clinical-scale manufacturing building. Ferguson Pape Baldwin Architects was tasked with creating a campus environment when Gilead acquired the adjacent building to house laboratories and office space. This parcel had limited parking and site area for utilities, so FPBA utilized its past experience in Oceanside to negotiate entitlement approvals with the local Business Park Association and obtain a Conditional Use Permit from the City for a reduced parking count. The new site improvements created pedestrian access and landscaping to tie the two buildings together and new glass storefront at the lobby entrance provided more natural light. The interior space was master planned to create a mezzanine for utilities and to preserve critical space for a future pilot plant, more labs and offices. Conference rooms, multi-purpose space, a cafeteria and fitness center were added to provide the amenities that had previously been lacking. The project was executed on an accelerated schedule in compliance with Gilead’s design standards. This project strengthens Gilead’s portfolio for research and development in Southern California with a strong base for recruiting of new staff and space for expansion to accommodate new functions. This project was a collaborative effort with BN Builders and a design-build team of engineers and contractors.
ViaSat, a leader in innovative satellite and wireless communication products for commercial and military markets, expanded to a seven building campus. FPBA were hired to relocate the Operations Group into a new facility that enhances their Operations’ efficiency, teamwork and cooperation. An newly upgraded entrance and lobby is the portal to and from the existing campus where manufacturing flows were utilized to organize an efficient, logical layout in as large an open manufacturing area as possible. FPBA developed 3D views and animations to enable the design team and users to create, understand and refine the all important physical aspects of the facility. An overhead modular grid system organizes the power, grounding, compressed air, phone and data to supply a multitude of possible manufacturing configurations. A meandering circulation path takes visitor and employees through an exciting open office area to conference rooms and other common areas while maintaining secure zones for ViaSat’s intellectual property.
As a 7,500-square-foot program component for the design of a larger cytology and oncology diagnostic facility, Genoptix required a certified CLIA (Clinical Laboratory Improvement Amendments) laboratory. Criteria included conformance to CDC’s Standards and Certification: Laboratory Requirements (42 CFR 493) issued by the Centers for Medicare & Medicaid Services (CMS), with particular design attention to criteria in Section 493.111, Facilities Administration. The design solution was coordinated with laboratory managers to ensure sample flows were uni-directional within the CLIA labs, that space planning segregated this function from other testing operations to avoid cross-contamination and that relative air pressurization and filtration was appropriate to the diagnostic procedures. CLIA inspections and subsequent certification were completed and achieved in Q4 2013.
Significant exterior and interior upgrades were designed by FPBA to BioMed Realty Trust’s facility at Road to the Cure, a 1980s vintage building located in La Jolla, California. The 68,000-square-foot building was completely renovated to include four upgraded laboratory spaces that take maximum advantage of both natural light and the landscaped views outdoors. Reconfigured laboratory suites respond to a variety of tenant needs to allow for maximum flexibility as end-user requirements evolve. The new conference center with contemporary audio visual capabilities is expandable to the exterior where outside meeting and gathering areas are carefully integrated with new landscape and site enhancements. The building’s exterior areas were designed as direct extensions of the interior upgrades, with new canopies visually expanding from the base building. The new technology-based fitness center provides tenants a welcome opportunity to enjoy physical activities away from their desk at any time during the day.
Nokia is a leading global company focused on the key growth areas of wireline and wireless telecommunications. A pioneer in mobile telephony, Nokia is the world’s leading developer of digital handsets and wireless data, the world’s second largest manufacturer of all mobile-phones, and one of the two leading suppliers of GSM-based cellular networks. The Nokia Creation Center in San Diego was designed according to the idea of connection; the connection to the landscape, connection to the sky, and the connection of people and ideas. Ferguson Pape Baldwin Architects created a site plan for the campus that encourages interaction among the various research, development and production personnel. FPBA invented an architecture that is as technologically derived as Nokia’s products and incorporated a water feature throughout the property that reflects the Finnish connection to water and serene environments. A result of this project is a multiple award-winning architecture that has quickly become a regional icon and immediate acceleration of Nokia’s ability to recruit engineers.
